Protein Info for Atu5393 in Agrobacterium fabrum C58

Annotation: LacI family transcription regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 PF00356: LacI" amino acids 14 to 58 (45 residues), 42.7 bits, see alignment 8e-15 PF00532: Peripla_BP_1" amino acids 71 to 313 (243 residues), 102.8 bits, see alignment E=5.1e-33 PF13407: Peripla_BP_4" amino acids 73 to 281 (209 residues), 39.3 bits, see alignment E=1.2e-13 PF13377: Peripla_BP_3" amino acids 178 to 336 (159 residues), 118.7 bits, see alignment E=5.7e-38

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to atu:Atu5393)

Predicted SEED Role

"LacI family transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D372 at UniProt or InterPro

Protein Sequence (341 amino acids)

>Atu5393 LacI family transcription regulator (Agrobacterium fabrum C58)
MESKDRLRQPRVTVHSVAAAAGVSKSTVSRILDERLPRSDSETAQRVREIAAELGYVRDV
SAANLRRGSTMTIGVIVPRLTDTVMAMLYEAIAKACTRSGRFAIVATTEDKPQADRLAAE
SLLNRGVDGLILSTARGDDDFPDELRERGVPYVLALRTDGHSLSAVGDDRLGGYLATRHL
LDLGHERIGVIAGPDYASSATGRVDGYRHALEEASISVDPQLIVPSTFGIQSGAEAIEKL
MGLGCRPTAIFAVNDNTAIGALSALSKMGISVPDDVSLVGYNDIPIVSHLPTPLTTLRVP
FDQIAANAIDLLTHTTALRDNRILVSAPTLIPRKSTARLGS