Protein Info for Atu5310 in Agrobacterium fabrum C58

Annotation: transmembrane sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 transmembrane" amino acids 77 to 94 (18 residues), see Phobius details PF16220: DUF4880" amino acids 11 to 53 (43 residues), 42.8 bits, see alignment 3.9e-15 TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 72 to 93 (22 residues), 19.1 bits, see alignment (E = 6.4e-08) PF04773: FecR" amino acids 109 to 200 (92 residues), 68.1 bits, see alignment E=7.4e-23

Best Hits

KEGG orthology group: K07165, transmembrane sensor (inferred from 100% identity to atu:Atu5310)

Predicted SEED Role

"Fe2+-dicitrate sensor, membrane component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CLD9 at UniProt or InterPro

Protein Sequence (311 amino acids)

>Atu5310 transmembrane sensor (Agrobacterium fabrum C58)
MLDENFEALRREATAWIVRITSGTATTEDAEALLRWRSRSDAHEQAFQQSARLWKNLGSA
LGETRKTSASTVTRRSFIAAGSVAAGAAGVGVVLSELGFLPSVDAMLADYATGVGEQRTV
ELVDGSTAILDGGTTLSLDYSPSSRHLVLTSGAAVFDVVHDAARPFVVTAANGDTTATGT
SFSVKHGEEDVSIECLEGHITVQCLGDSQLNGGEGISYSRAGLGKKVAADIETAAAWRRG
LLIFEDRPLADVVSDLNRHRRGRVVIASSDLRSRRMSGVFHLNRPDEILAHLEETLQVRP
VSLVGGIVLLR