Protein Info for Atu5085 in Agrobacterium fabrum C58

Annotation: metallo-beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00753: Lactamase_B" amino acids 88 to 260 (173 residues), 73.6 bits, see alignment E=1.1e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu5085)

Predicted SEED Role

"SoxH protein, homolog" in subsystem Sulfur oxidation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D3Y3 at UniProt or InterPro

Protein Sequence (319 amino acids)

>Atu5085 metallo-beta-lactamase (Agrobacterium fabrum C58)
MPSRRSILKSALTGLVAAPFVAPSLTFAKAPYAVVQAPGFYRLKIGSVEVTALSDGTIPL
PLSKLYTNTSQQHAQSVLSDAFLPASVPTSVNAFLVNTGDRLVLIDAGTGTYIGPSLGKL
AANIEASGYKVDDIDDVVLTHIHTDHSGGLVSNGKRSFPNATLRVNEREAKFWLSADNAN
AATGIVKQQFAEADQCVTPYVKAEKFETFADNAAPVPGLGSILYAGHTPGHSAITLESEG
QKIVFWGDITHGDILQFDEPGVAIEFDIDQKAAVAARDIAFKQAVEGRYLVGGAHIAFPG
IGHVRKDSTNYDWLPINYA