Protein Info for Atu4786 in Agrobacterium fabrum C58

Annotation: iron ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 PF00005: ABC_tran" amino acids 26 to 166 (141 residues), 128.7 bits, see alignment E=2.5e-41 PF08402: TOBE_2" amino acids 280 to 343 (64 residues), 34.3 bits, see alignment E=2.1e-12

Best Hits

Swiss-Prot: 100% identical to FBPC_AGRFC: Fe(3+) ions import ATP-binding protein FbpC (fbpC) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02010, iron(III) transport system ATP-binding protein [EC: 3.6.3.30] (inferred from 100% identity to atu:Atu4786)

Predicted SEED Role

"Ferric cations import ATP-binding protein fbpC (EC 3.6.3.30)" (EC 3.6.3.30)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.30

Use Curated BLAST to search for 3.6.3.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U6M1 at UniProt or InterPro

Protein Sequence (353 amino acids)

>Atu4786 iron ABC transporter ATPase (Agrobacterium fabrum C58)
MITVKPGSVVFENVRKTFGAFTAIPDLSLTIEPGTLVTLLGPSGCGKTTTLRMLAGLEHP
NSGRILIGGKDVTMLPANERDVSMVFQSYALFPHMSALDNVAYGLQSSGLKKAEAREKAE
EGLKLVGLAGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTD
IRELQQRIGFTAVYVTHDQDEALAVSDRIIVMKEGEIAQSGAPRELYEAPASSFIADFMG
EANVVPCEVVSQTGDESLVRVGTMEHRVRSRGPRSGSAKLAVRPGAITIGAAGGSGMPGR
VLHTAYLGGHIEYEVETEVGTLFIIDHEMNHTQRETSDVTLNFKNRGIALIDA