Protein Info for Atu4784 in Agrobacterium fabrum C58

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13531: SBP_bac_11" amino acids 39 to 284 (246 residues), 60.9 bits, see alignment E=3.2e-20 PF01547: SBP_bac_1" amino acids 43 to 280 (238 residues), 72.4 bits, see alignment E=1.3e-23 PF13416: SBP_bac_8" amino acids 43 to 298 (256 residues), 87.9 bits, see alignment E=2.2e-28 PF13343: SBP_bac_6" amino acids 90 to 316 (227 residues), 96 bits, see alignment E=5.3e-31

Best Hits

Swiss-Prot: 47% identical to Y131_HAEIN: Uncharacterized protein HI_0131 (HI_0131) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 100% identity to atu:Atu4784)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CVV2 at UniProt or InterPro

Protein Sequence (341 amino acids)

>Atu4784 ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MRLTIISSLLLAGTTLLGVPAHAAGDLNLICAADVVICEQMKGDFEKTHDIKVNMVRMSS
GEAYAKIRAEARNPKTDLWWAGTGDPHLQAASENLTLEYKSKMLDQLQDWAKNQAESAGY
KTVGVYAGALGWGYNTDIFKKKGYKEPKCWADLLAPELKGEIQIANPNSSGTAYTALASL
VQIMGEDQAFDYLKKLNGNISQYTKSGSAPVKAAARGETAVGIVFMHDAVAQTAEGFPVK
SVAPCEGTGYEIGSMSIVKGARNLENAKTWYDWALQPDVQSRMKDAKSFQLPSNKTAEIP
KEAPRFEDIKLINYDFKTYGDPEKRKALLERWDKDVGAAAN