Protein Info for Atu4755 in Agrobacterium fabrum C58

Annotation: amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR02995: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB" amino acids 3 to 280 (278 residues), 458.7 bits, see alignment E=3.2e-142 PF00497: SBP_bac_3" amino acids 36 to 262 (227 residues), 100.3 bits, see alignment E=3.7e-33

Best Hits

Swiss-Prot: 50% identical to Y4TE_SINFN: Probable amino-acid ABC transporter periplasmic-binding protein y4tE (NGR_a01540) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to atu:Atu4755)

Predicted SEED Role

"amino acid ABC transporter, periplasmic amino acid-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CH32 at UniProt or InterPro

Protein Sequence (283 amino acids)

>Atu4755 amino acid ABC transporter substrate-binding protein (Agrobacterium fabrum C58)
MNMTKLAGLSALALIIGVTSASALTLEEVKKQGYIRAATANEVPYSYMQPDGTSAGIGPD
VANAVLKSMGIEEVNWTVTPFGTLIPGLKARRFDFAAAEQNISPERCKQVAFTEPNSSYG
EGLLVKKGNPKKLTTYADIAKDPALKVAVVSGANNVDFLRAVGVKEEQIVFIPANADAIP
TVQSRADAYAATELTVSELAKGQANVEQVKPFVDPVVKDAPVRNYGGFAFRPEDKELRDA
FNTALVEFRKTDDYKKILAKYGLSEQSIAAAAEKKVADLCAGK