Protein Info for Atu4745 in Agrobacterium fabrum C58

Annotation: sugar ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF00005: ABC_tran" amino acids 22 to 173 (152 residues), 102.2 bits, see alignment E=3.9e-33 amino acids 273 to 426 (154 residues), 90.3 bits, see alignment E=1.9e-29

Best Hits

Swiss-Prot: 41% identical to RBSA_JANSC: Ribose import ATP-binding protein RbsA (rbsA) from Jannaschia sp. (strain CCS1)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to atu:Atu4745)

Predicted SEED Role

"Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CVR4 at UniProt or InterPro

Protein Sequence (496 amino acids)

>Atu4745 sugar ABC transporter ATPase (Agrobacterium fabrum C58)
MSAEPLLSLKNVKVTFGGVRALKGVSFEVNPGEVHCLAGENGCGKSTVIKVITGVYKPES
DAELYFDGKPIAAMTPTLAQSLGIQVIWQDLALFDEMTVAENIGFQYAVNGRFGLVDKRA
IKNAAEKALARLGVSFDLDRPLKELPIAQRQIVAIARALVGEARLVFMDEPTASLTQSET
DYLIDIVRNLSASGVAVVFVSHRLAEVLEISDRITVLRDGSLVGVFPVEGMTQSRVTELM
TGRNFDSAVIAADHDDKPVVLSVRGLTRAGEFEDVSFDLRRGETLGITGLLGAGRTELAL
TLFGMHRPQSGEVLIDGKKVDFHSNRDAIRVGVAYLSEDRLSLGLNQPQSIADNLVMASL
DKLLSGGLISTSKKADVVSRWISALGVKIGLPEDPIRTLSGGNQQRVAIAKWLAIGPKIL
ILDAPTVGVDVGARAGIFEIVRKLAAEGLSIIVISDEAPEVYFNTDRVIHMVEGRFHATY
DPRRLSLTELEAAIYA