Protein Info for Atu4741 in Agrobacterium fabrum C58

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 PF00158: Sigma54_activat" amino acids 333 to 496 (164 residues), 206.7 bits, see alignment E=4e-65 PF14532: Sigma54_activ_2" amino acids 333 to 502 (170 residues), 70.5 bits, see alignment E=3.6e-23 PF07728: AAA_5" amino acids 354 to 474 (121 residues), 28 bits, see alignment E=4.1e-10 PF02954: HTH_8" amino acids 590 to 620 (31 residues), 38.5 bits, see alignment (E = 1.6e-13)

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4741)

Predicted SEED Role

"Transcriptional activator of acetoin/glycerol metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CH23 at UniProt or InterPro

Protein Sequence (627 amino acids)

>Atu4741 transcriptional regulator (Agrobacterium fabrum C58)
MGFSDHIKEIETVGQGRNTGRDAVVLESWRRCLDTYQLDPTKAREAVIVSETRLREHRQQ
AEDLLHIARSGLERLYRQVAEQNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWS
EPRAGTCAVGACIATGESLTIHQTDHFDVTHTPLSCTAAPIYDTQGALTAVLDISLLSSP
ILKTSQNMARHLVSSTVRRIELANLMASSRHDLVLRFAGAPEFLDVDPEAALSVDGSGRI
TGMTHAAARLLAASRGLDWRMPERLLGQRVEEFFEAGLDELASLTRSSLPQDRRIVVRDG
TVLYAHAIEPQQRRSSVPLARSKPQPVTERIGGDGPAVRNLRRKVEKLSPARLPILLQGQ
TGTGKEHLARIIHDASGVSGRFVAVNCAAIPEQLIESELFGYLPGAFTGALAKGRKGLVE
EAQGGTLFLDEIGDMPFAAQSRLLRVLAEGEVLPVGGSTPQKVDFRVISASHRPLNDMVR
TGAFREDLYYRLNAAVLTLPALSERDDFPWLLDRILEKHGMPGRPLTLSNAARLTILHHR
WPGNIRELDNAIAFAAALCDDGLITVEDLPEQLTPASSTPMIDSRGTDLRALLAACNGNI
SEAARRLGVDRTTLHRRMRRLGIGKPH