Protein Info for Atu4597 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 transmembrane" amino acids 68 to 88 (21 residues), see Phobius details amino acids 95 to 121 (27 residues), see Phobius details amino acids 127 to 146 (20 residues), see Phobius details amino acids 175 to 201 (27 residues), see Phobius details amino acids 222 to 241 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 75 to 246 (172 residues), 101.3 bits, see alignment E=2.9e-33

Best Hits

KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 100% identity to atu:Atu4597)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, transmembrane component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGV6 at UniProt or InterPro

Protein Sequence (267 amino acids)

>Atu4597 ABC transporter permease (Agrobacterium fabrum C58)
MFSKILGAVKGQTHTIGSLVGAGIVWEIAVRALKVPEYILPAPSRVFADLYNNVPVVFTA
SLYTLQPMVLGFLVAVVMGTLLALLVVYSRAFEAIFYPLLVILQIIPKIAIAPLFIIWVG
FGLPSKILLVFLLSFFPIVVNSIVAFKSIEPDVYDLAKSYRAGRLKIFWKVELPGALPSL
FAGFKVAAALSATAAVVAEFVASDNGLGYLLLNYNGNMNTSMTFAVIIVLSLLGLLLYGI
VELIERFAIPWHVSQRREDFTVGKSTT