Protein Info for Atu4550 in Agrobacterium fabrum C58

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 PF00356: LacI" amino acids 5 to 48 (44 residues), 55 bits, see alignment 5.6e-19 PF13407: Peripla_BP_4" amino acids 67 to 300 (234 residues), 96.1 bits, see alignment E=2.8e-31

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to atu:Atu4550)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CV86 at UniProt or InterPro

Protein Sequence (342 amino acids)

>Atu4550 LacI family transcriptional regulator (Agrobacterium fabrum C58)
MKRPTITDVAKAAGVSVATVDRVLNGRLPVREETARRVFEAAEKIGFHAANIIRQRMLAD
MPSYSLGIILRKERHAFYQTFADELELAARNIRDRHLNLRIEFAQSGEPGELAGLLTGMK
GRVQAVAATGPDHHDVTAAVEALKAKGIPTFSLLSDFAQGVREAYLGANNMKVGRTAAWM
ISRLARGKGKVLLLLGGHRFHGHSLRETGFRSYMREYAPEFEVMDALITLETRRLSYELV
MDTIAKHRDLVGIYCIGGGMEGVIEALQQENRQEDIVCLVNELTPESRQALLERRISGVF
QTPLRELCTDLLTTMVHTIEHGMAETPGQRFVPAHLWVPESL