Protein Info for Atu4498 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 73 to 93 (21 residues), see Phobius details amino acids 114 to 140 (27 residues), see Phobius details amino acids 152 to 171 (20 residues), see Phobius details amino acids 249 to 272 (24 residues), see Phobius details amino acids 278 to 305 (28 residues), see Phobius details amino acids 325 to 346 (22 residues), see Phobius details PF03824: NicO" amino acids 77 to 347 (271 residues), 275.7 bits, see alignment E=2.4e-86

Best Hits

KEGG orthology group: K08970, nickel/cobalt exporter (inferred from 100% identity to atu:Atu4498)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGR1 at UniProt or InterPro

Protein Sequence (349 amino acids)

>Atu4498 hypothetical protein (Agrobacterium fabrum C58)
MLSRRASLAAIAIGLIAAAGAAHAQSPLGIGSAEPSFSLGGPFAPLMQWINVHQQMFYRA
LTGALKAMREDSWALGSLIGLSFAYGVFHAAGPGHGKAVISSYMIANETQLRRGILISFV
SALIQGLMAIGLVGAAWLVLRGTSITMTKATQAMEIASFAMVALFGAWLLVRKLWSLRIR
REPVPVFATAGEAPAARTNGMGTGLRFQGKPVFADHDHNGTGDLCTACGKSHAPDPMLLK
GKNFSLHEAWSAIIAVGLRPCSGAIIVMSFALLNGLYLGGVLSVLAMSLGTAITVSALAI
MAVSAKGLAVRFAGPGSRKAAGISHAIEIAGALFVLIMGLLLLGASLQF