Protein Info for Atu4481 in Agrobacterium fabrum C58

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF00356: LacI" amino acids 4 to 48 (45 residues), 55.8 bits, see alignment 3.1e-19 PF13407: Peripla_BP_4" amino acids 65 to 319 (255 residues), 138.9 bits, see alignment E=2.3e-44

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to atu:Atu4481)

Predicted SEED Role

"Novel Xylose regulator from LacI family" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGQ7 at UniProt or InterPro

Protein Sequence (340 amino acids)

>Atu4481 LacI family transcriptional regulator (Agrobacterium fabrum C58)
MKPTVHDIAERAGVSLATIDRVLNMRPGVHAATRARVEAAIAELGYVRDIAAANLAKGRN
YSMIFILPGNDNSFMATLRAEVRAAAGRSHLERTAIRVIEVPPFNAAALTEALEVARREK
PSGVAFVATDSEDVAEAADRLAEDGIATVTLVSDLSGSRRDHYAGVDNVAAGRTAASLMG
RFLSGHGGDVAVVAGSMLVRDHRERLEGFRAVLETEFPQVRLLPVLEGRDDPLTVEALVR
EAIGNDSLAGIYSLGAGNRGLIRALGAADGERALSVIAHELTENTANALREGLLDAVLNQ
DAGHEVRSAIRVLKARADGLPVIAAQERIRIDIFLRDNLP