Protein Info for Atu4469 in Agrobacterium fabrum C58

Annotation: iron ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 56 to 83 (28 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 135 to 153 (19 residues), see Phobius details amino acids 174 to 191 (18 residues), see Phobius details amino acids 197 to 214 (18 residues), see Phobius details amino acids 221 to 241 (21 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details PF00950: ABC-3" amino acids 11 to 265 (255 residues), 274.4 bits, see alignment E=1e-85 PF01032: FecCD" amino acids 65 to 262 (198 residues), 33.7 bits, see alignment E=2.1e-12

Best Hits

Swiss-Prot: 64% identical to YFEC_YERPE: Chelated iron transport system membrane protein YfeC (yfeC) from Yersinia pestis

KEGG orthology group: K11605, manganese/iron transport system permease protein (inferred from 100% identity to atu:Atu4469)

Predicted SEED Role

"Manganese ABC transporter, inner membrane permease protein SitC" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CV14 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Atu4469 iron ABC transporter permease (Agrobacterium fabrum C58)
MINSLLEPFTYGYMLNAIWVSALVGGVCGFLSAYLMLKGWSLIGDALSHAIVPGVAGAYM
LGLPFSLGAFLSGGLAAGSMLFLNQKTRLKEDAIIGLIFTSFFGLGLFMVSLSPTSVNIQ
TIVLGNILAITAEDTIQLALIGGISLLVLALKWRDFMVVFFDENHARTVGLKPEVLKVIF
FTLLAASTVAALQTVGAFLVVAMVVTPGATAYLLTDRFERLILMSLIIGAATSFVGAYLS
YFLDGATGGVIVVLQTAIFLAAFVFAPKHGLLASRAKARKALEETP