Protein Info for Atu4424 in Agrobacterium fabrum C58

Annotation: spermidine/putrescine ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 PF00005: ABC_tran" amino acids 22 to 164 (143 residues), 131 bits, see alignment E=4.8e-42

Best Hits

Swiss-Prot: 48% identical to FBPC_BRUA2: Fe(3+) ions import ATP-binding protein FbpC (fbpC) from Brucella abortus (strain 2308)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 100% identity to atu:Atu4424)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGM3 at UniProt or InterPro

Protein Sequence (341 amino acids)

>Atu4424 spermidine/putrescine ABC transporter ATPase (Agrobacterium fabrum C58)
MSDANYLSLNKVSLAYGNSIAVKDLDLDIRKGELLALLGPSGCGKTTTMRAIAGLMPVAS
GRIDLDGADITRVAANKRAVGLVFQSYALFPHLTVYENVAFGLKLKGMSGKTLDDKVASG
LKSVGLSNFASRKPAELSGGQQQRVALARSMVMEPKVLLLDEPLSNLDARLRLEMRTELQ
RVQKETGVTMIFVTHDQIEALALADRIVVMKGGKIEQIGTPEEIYNAPVSSFVADFVGFE
NIFALEDGALKTANGKTSLTGPVPSASGLAWRPRMVTLGSGPFQGTVRGTSFAGNSREYL
LDTPLGAIKAETDAALAAHAIGDTLAFDLPVEKAASLKVFN