Protein Info for Atu4410 in Agrobacterium fabrum C58

Annotation: periplasmic nitrate reductase, cytochrome c-type protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR02161: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family" amino acids 12 to 195 (184 residues), 316.5 bits, see alignment E=3e-99 PF03264: Cytochrom_NNT" amino acids 23 to 194 (172 residues), 254.8 bits, see alignment E=7.4e-80

Best Hits

Swiss-Prot: 76% identical to NAPC_PARPN: Cytochrome c-type protein NapC (napC) from Paracoccus pantotrophus

KEGG orthology group: K02569, cytochrome c-type protein NapC (inferred from 100% identity to atu:Atu4410)

Predicted SEED Role

"Cytochrome c-type protein NapC" in subsystem Nitrate and nitrite ammonification or trimethylamine N-oxide (TMAO) reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGL6 at UniProt or InterPro

Protein Sequence (233 amino acids)

>Atu4410 periplasmic nitrate reductase, cytochrome c-type protein (Agrobacterium fabrum C58)
MMIARIKKLFIWLWAVLTTPAGTLSLAFLTLGGFVGGVMFWGAFNTALEMTNKEAFCISC
HEMRANVYEELTRTVHFSNRSGVRASCPDCHVPHEWTDKIARKMQASKEVWGKIFGTIDT
RKKFLDKRLELAQHEWSRLKANDSLECRNCHSSVAMDFTKQTQRAADIHSKYLLTGKATC
IDCHKGIAHELPNMEGIDPGWKMPPALNDEPGQTASAVDDLRRAMSDVHRNVF