Protein Info for Atu4395 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04343: DUF488
  • amino acids 5 to 113 (109 residues), 119.6 bits, E=6.3e-39

Best Hits

Swiss-Prot: 49% identical to YEAO_ECOLI: Uncharacterized protein YeaO (yeaO) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to atu:Atu4395)

Predicted SEED Role

"probable uroporphyrin-III c-methyltransferase (EC 2.1.1.107)" (EC 2.1.1.107)

MetaCyc Pathways

• adenosylcobalamin biosynthesis II (aerobic) (29/33 steps found)
• cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) (12/13 steps found)
• cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion) (12/15 steps found)
• siroheme biosynthesis (4/4 steps found)
• adenosylcobalamin biosynthesis I (anaerobic) (26/36 steps found)
• factor 430 biosynthesis (3/7 steps found)

KEGG Metabolic Maps

• Porphyrin and chlorophyll metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.107

Use Curated BLAST to search for 2.1.1.107

Sequence Analysis Tools

See Q7CUU4 at UniProt or InterPro

Protein Sequence (116 amino acids)

>Atu4395 hypothetical protein (Agrobacterium fabrum C58)
MSDIRIKRIYEPASDDDGTRVLVDRLWPRGMRKEDAKLSLWMKEIAPSNELRKQFSHMPS
RFADFTGHYHQELSANPDAVARMKELMAKGRVTLLYAAHDTEHNHALVLADYLHSH