Protein Info for Atu4366 in Agrobacterium fabrum C58

Annotation: short chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 PF00106: adh_short" amino acids 9 to 197 (189 residues), 106.1 bits, see alignment E=2.6e-34 PF08659: KR" amino acids 10 to 185 (176 residues), 41.5 bits, see alignment E=2.1e-14 PF13561: adh_short_C2" amino acids 18 to 255 (238 residues), 139.9 bits, see alignment E=1.6e-44

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4366)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGI4 at UniProt or InterPro

Protein Sequence (257 amino acids)

>Atu4366 short chain dehydrogenase (Agrobacterium fabrum C58)
MTDHSLKGKTVIIAGGAKNLGGLIARDFAAQGAGAIAIHYNSAASRADADATVAAVKAAG
AEAIALQADLTTAGAVEKLFADAVAAIGRPDIAINTVGKVLKKPILETSEAEYDEMTAVN
AKSAFFFLQQAGRHVSDNGKICTLVTSLLGAFTPFYASYAGTKAPVEHFTRAAAKEFGER
GISVTAIGPGPMDTPFFYGQETPEAQGYHKTAAALSAFSKTGLTDIEDIVPYIRFLVTDG
WWMTGQTILVNGGYTTK