Protein Info for Atu4304 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 61 (22 residues), see Phobius details amino acids 75 to 100 (26 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 139 to 156 (18 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 158 to 225 (68 residues), 43.5 bits, see alignment E=2.8e-15 PF00027: cNMP_binding" amino acids 368 to 450 (83 residues), 60.1 bits, see alignment E=1.7e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4304)

Predicted SEED Role

"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGE5 at UniProt or InterPro

Protein Sequence (496 amino acids)

>Atu4304 hypothetical protein (Agrobacterium fabrum C58)
MLQAYMGEIAAAPLAWLIILGLAGMAVWKRIGSQRSNLRLVVQIAFFGAMTSVLVLGKIP
LGPPKDLWTGDEHAVFIVFAQLLWWLHLSWAVIGFVRIYLVLEGRPREARLLQDIVVGVV
YVCVTLSALAFVFGVPVGTLVATSGVIAIALGLALQNTLGDVFSGVALNLGHTYALGDWI
LLEDGTEGRVIASTWRSTQILTGANNIVVLPNSVLAKLKLTNVSRPDETHLLKMTVRLVP
THAPSMIEEAMTTVLAGCNSIMREPPPLVSMSGLDATALEIHLFFRVSNPMLRIKAQNEV
IDRFYRHCRSIGLQLAMPPSAIAIMNGVASTEISRRAEATLQEVIDENPILSRLTRAERE
KLAQSGSEREYRQGEVIVVEGQALPSMMIIRTGVVSMQHGEQEKRRLSPGDFFGETGLLA
GMGEAYTLLALTRVTAYEIDQKSFARLIADRPAIAEEVTTMLLASSGNVSQLPLTQAKHE
RNASAFLKSIRTIFST