Protein Info for Atu4272 in Agrobacterium fabrum C58

Annotation: acetyl-CoA carboxylase biotin carboxyl carrier protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 PF00364: Biotin_lipoyl" amino acids 73 to 146 (74 residues), 66.2 bits, see alignment E=1.9e-22

Best Hits

KEGG orthology group: K02160, acetyl-CoA carboxylase biotin carboxyl carrier protein (inferred from 100% identity to atu:Atu4272)

Predicted SEED Role

"Biotin carboxyl carrier protein of acetyl-CoA carboxylase" in subsystem Fatty Acid Biosynthesis FASII

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CGC6 at UniProt or InterPro

Protein Sequence (147 amino acids)

>Atu4272 acetyl-CoA carboxylase biotin carboxyl carrier protein (Agrobacterium fabrum C58)
MDLPKIKTLIDFVGRTNVTELTVTEKKVTVRIFRTVGQSATIAETNSTEGEVAGPASSAD
VSTSVVSAGSTFTVKAPVFGVLHRSPTPGQKPFVNVGDRVEEGQTLFIIEAMKVFNTIAA
PHAGRIAYLTEVDGGEVETGDVLAEIA