Protein Info for Atu4171 in Agrobacterium fabrum C58

Annotation: cold-shock dead-box protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 PF00270: DEAD" amino acids 24 to 195 (172 residues), 148.9 bits, see alignment E=2.4e-47 PF04851: ResIII" amino acids 36 to 190 (155 residues), 25.4 bits, see alignment E=2.5e-09 PF00271: Helicase_C" amino acids 234 to 339 (106 residues), 94.3 bits, see alignment E=1.1e-30 PF03880: DbpA" amino acids 470 to 538 (69 residues), 52.2 bits, see alignment E=1e-17

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to atu:Atu4171)

Predicted SEED Role

"FIG003033: Helicase domain protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CG67 at UniProt or InterPro

Protein Sequence (615 amino acids)

>Atu4171 cold-shock dead-box protein A (Agrobacterium fabrum C58)
MTDTQGIAPAIAQALEKRGYKDLTPVQQAMLAPELANKDALVSAQTGSGKTVAFGIALAT
TLLSENTRFGQASAPLALAIAPTRELAMQVKRELEWLYEFAGVSIASCVGGMDIRNERRA
LERGAHIVVGTPGRLCDHIKRNALDLSSIRAVVLDEADEMLDLGFREDLEFILEESPDDR
RTLMFSATVPRSIAKLAESYQKNAVRIATASEQKQHVDIEYRALLVSPSDRENAIINALR
FYEARNAIVFCSTRAAVNHLTARLNNRGFSVVALSGELTQNERTHALQAMRDGRARVCVA
TDVAARGIDLPGLELVIHADLPTNSETLLHRSGRTGRAGQKGVSAIVVPVSQRRKAERLL
EGAKVSAAWVRPPSVEEIVERDGARLLADPTLSEAVTDDERDFVNKLLEQHGAEKVAAAF
VRLYHSGRSAPEDIFEVALDNTRKPRRDSFETTENNAPRRDRSDFSDSAWFSLSVGRKQS
AEPRWLIPMLCRFGKITRQDIGAIRMQQTETFVELAADAVDRFTSAIGKDMMLEKGIRLK
QMEGKPEMTGNAREDTRPATAQRKFTKSDNAGAPRDDRKADDKPWKKKKAFGDKPKYEGK
KDKPFEKRGPKPTKG