Protein Info for Atu3910 in Agrobacterium fabrum C58

Annotation: LamB/YcsF family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03746: LamB_YcsF
  • amino acids 4 to 241 (238 residues), 342.4 bits, E=7.8e-107

Best Hits

Swiss-Prot: 100% identical to PXPA1_AGRFC: 5-oxoprolinase subunit A 1 (pxpA1) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K07160, UPF0271 protein (inferred from 100% identity to atu:Atu3910)

MetaCyc: 40% identical to 5-oxoprolinase component A (Escherichia coli K-12 substr. MG1655)
5-oxoprolinase (ATP-hydrolyzing). [EC: 3.5.2.9]

Predicted SEED Role

"Lactam utilization protein LamB"

MetaCyc Pathways

• γ-glutamyl cycle (5/6 steps found)
• 5-oxo-L-proline metabolism (4/6 steps found)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

See Q8U920 at UniProt or InterPro

Protein Sequence (255 amino acids)

>Atu3910 LamB/YcsF family protein (Agrobacterium fabrum C58)
MAAIDLNSDLGESYGAWRMGDDEAMLAIVSSANIACGFHAGDPAGIYRTVKAAAEKGVVV
GAHVSYPDRVGFGRRDLDATSEELIADVIYQIGALKGVAAAAGTTVRYVKPHGALYNRIA
NDAKQGQAVIDGIKAIDPSLVLMGLANAPILDLARKAGLAVVAEAFADRAYTPEGQLVSR
REAGAVLHDAAKIAERMVQLAREGTLEAIDGSIIKIEAQSICVHGDSPGAVAIAQEIRRR
FEADGIAIRSFASDR