Protein Info for Atu3698 in Agrobacterium fabrum C58

Annotation: thioredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 PF00085: Thioredoxin" amino acids 35 to 137 (103 residues), 92.9 bits, see alignment E=3.5e-30 TIGR01068: thioredoxin" amino acids 50 to 137 (88 residues), 104.2 bits, see alignment E=1.8e-34 PF13098: Thioredoxin_2" amino acids 51 to 134 (84 residues), 31.1 bits, see alignment E=7.8e-11 PF14559: TPR_19" amino acids 160 to 221 (62 residues), 63.1 bits, see alignment E=7.3e-21 PF14561: TPR_20" amino acids 233 to 321 (89 residues), 95.8 bits, see alignment E=4.9e-31

Best Hits

KEGG orthology group: K05838, putative thioredoxin (inferred from 100% identity to atu:Atu3698)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CT41 at UniProt or InterPro

Protein Sequence (322 amino acids)

>Atu3698 thioredoxin (Agrobacterium fabrum C58)
MSDTNNPYGGSYGGQMTASAHHNGELNGAASGHIKDTTTAGFSKDVLEESRRQPVLVDFW
APWCGPCKQLTPVLEKVINEANGRVKLVKMNIDDHPSIPGQLGIQSIPAIVAFADGRPVD
GFMGAVPESQIRQFIDKIAGPDAGDPKAEIEAALSEAKQLLADGDFNGAAQLFGAVMQAD
PENPAAIAGIAECMIAAGQYERASELLSSLPAELNDDAGIQLVSKKIAQYEEARKIGDPV
ALERDLAQNPDHHEARVKLAKVLNAQGRRDEAADHLLYVMRKDRTFDDDGARRQLLEFFE
SWGFKDPASIAGRRKLSAILFS