Protein Info for Atu3634 in Agrobacterium fabrum C58
Annotation: penicillin-binding protein dacf precursor
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01286, D-alanyl-D-alanine carboxypeptidase [EC: 3.4.16.4] (inferred from 100% identity to atu:Atu3634)Predicted SEED Role
"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)
MetaCyc Pathways
- peptidoglycan biosynthesis II (staphylococci) (12/17 steps found)
- peptidoglycan biosynthesis IV (Enterococcus faecium) (12/17 steps found)
- peptidoglycan maturation (meso-diaminopimelate containing) (3/12 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.4.16.4
Use Curated BLAST to search for 3.4.16.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q7CSY9 at UniProt or InterPro
Protein Sequence (389 amino acids)
>Atu3634 penicillin-binding protein dacf precursor (Agrobacterium fabrum C58) MVNIAIPRLKTGIRGLALPNTVKSPNAARRLSAAIAIVTAGVVAVAPVANANPKMVVDVK TGKVISHQEAFRKWYPASLTKLMTAYIAFSQMKAGKISPQTEVVMSKKAADQPASKMYFK PGQKLTMDSALKLLLIKSANDIAVAIAETIGGTSDNFVAQMNAQAQRLGMSSTHYVNPNG LPGKGQYTTARDLALLALIIKREFPEYAHYFSLEGVTTGKKNYANFNMLVGRFEGADGMK TGFICASGFNQVASAVRNGRSVITVVLGADSLAGRTDQSADLLQMGLTAPSGQGVSLASL APYGDTAEVNDISAEICNPKAAKVRSEGRDEAGRMVIHSPYVTEMTRPPEYSFAGLIPGS ETVAVNAPKGAAGKGQLANVPIPIPRPTF