Protein Info for Atu3458 in Agrobacterium fabrum C58

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 92 to 118 (27 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 157 to 173 (17 residues), see Phobius details amino acids 212 to 237 (26 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details PF12911: OppC_N" amino acids 25 to 68 (44 residues), 42.8 bits, see alignment 3.9e-15 PF00528: BPD_transp_1" amino acids 109 to 290 (182 residues), 102.6 bits, see alignment E=2.3e-33

Best Hits

Swiss-Prot: 48% identical to DDPC_ECOLI: Probable D,D-dipeptide transport system permease protein DdpC (ddpC) from Escherichia coli (strain K12)

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to atu:Atu3458)

MetaCyc: 40% identical to nickel ABC transporter membrane subunit NikC (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CF91 at UniProt or InterPro

Protein Sequence (295 amino acids)

>Atu3458 ABC transporter permease (Agrobacterium fabrum C58)
MTARAETSSRLPVPLNALKNIILFLLKSPTSAFGLAVLLLLVIAAIFAPWLATHDPYAQD
LANTLQAPGNGHVFGTDELGRDIYSRLLWGARITLTIISLVSIIVGPVGLLVGTASGYLG
GKFDTVMMRITDIFLSFPSLILSLAFVAALGPSLNNAIIAIALTSWPPIARLARAEAMTF
RKADYIAAARLQGASPLRIIVKSIMPMCLPSVLIRLTLNMATVILTAAGLGFLGLGAQPP
LPEWGAMIATGRRYMLDSWWLVTFPGVAILSVSLAFNLLGDGLRDALDPKQMNRR