Protein Info for Atu3394 in Agrobacterium fabrum C58

Annotation: iron ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 PF00005: ABC_tran" amino acids 19 to 167 (149 residues), 122.6 bits, see alignment E=2e-39

Best Hits

Swiss-Prot: 39% identical to FHUC_ECOLI: Iron(3+)-hydroxamate import ATP-binding protein FhuC (fhuC) from Escherichia coli (strain K12)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 100% identity to atu:Atu3394)

MetaCyc: 39% identical to iron(III) hydroxamate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-11-RXN [EC: 7.2.2.16]; TRANS-RXN-297 [EC: 7.2.2.16]; TRANS-RXN-298 [EC: 7.2.2.16]

Predicted SEED Role

"Copper ABC transporter, ATP-binding component"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34 or 7.2.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CF51 at UniProt or InterPro

Protein Sequence (266 amino acids)

>Atu3394 iron ABC transporter ATPase (Agrobacterium fabrum C58)
MKLFAHDLHFHAGNIDIVRGVSFDVGSGEFLGIIGPNGSGKSTLLSMLAGIRKPRRGHVT
LGEEPLGSLGRRDLARRLAFVEQQAETTERITARQAVELGRTPYLGPLSAWSQNDDAVVD
AALANVDMADKAERSWHHLSGGERQRLHIARALAQEPHILLLDEPTNHLDIGHQIGLLDL
VRRQGLTVVAALHDLNHAAMFCDRVAILHRGEMIAVGPPREVLTAATIADVFGVKCAVTT
DEGGFSHIRFLPAHGRADPARKVLAR