Protein Info for Atu3385 in Agrobacterium fabrum C58

Annotation: heme receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 923 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF07660: STN" amino acids 88 to 128 (41 residues), 30.7 bits, see alignment (E = 3.3e-11) TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 148 to 923 (776 residues), 844.3 bits, see alignment E=7.4e-258 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 150 to 923 (774 residues), 576 bits, see alignment E=1.2e-176 PF07715: Plug" amino acids 175 to 290 (116 residues), 56.1 bits, see alignment E=7.3e-19 PF00593: TonB_dep_Rec" amino acids 382 to 896 (515 residues), 152.2 bits, see alignment E=6.4e-48

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to atu:Atu3385)

Predicted SEED Role

"Iron siderophore receptor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CSB9 at UniProt or InterPro

Protein Sequence (923 amino acids)

>Atu3385 heme receptor (Agrobacterium fabrum C58)
MRLQICRTGSGEKTAGQTRRAVLLATTAIAISFAPPVLAQTGADAANSRQPGGEQGATRP
FNIPAQSLSSVVSAFGRQSDLQVTLATPAAGNVRTNAVAGSFTVREALSRLLAGTGVNFR
IAGNGRTVIIGTGESTVDFSEAAGTTVLETITVTGKSGRNSLAGAGYQGTPDWVYDTPAS
VSVVSREAIQSAGVRNTRDVFNRVSGVYAGEGNGSFPTVSPNVRGLQESGRVVVSIDGAR
QNAQRGYSTGGASIYSANNGQAYVDAAFIRAVEVEKMTSATSGNAGSLGGKVEFRTVSAA
DLIPEGANKGAEVNVSRGSNGYDFQGSVLAAVREPDGPLSFVAGYSRTIMDEYKIGTKGE
ALSTALTMKDLLGRDGWSTFFKSEGDFGDVQTSLSWMHQQNDFVQGASTVVDREGVRNDS
IVAKLDWDPESELIDFKSSLWLNDNMTHELRAARTYAVETNLDMGLRSFGGSLENTSRFD
TRAGALSLNYGAEAFRDIATSVATSATIAQNPSFASSYTSFSPAGRRDVASLFLNGELEP
ADWITLSGGVRYDWSRLKGSATYYSFKESIVTTSVPCDLVRNHYTALEYFNQVFLPANLP
VWASRYNVFLASIWPRTSANCMPGTGITTKTPVTEYPSHEVDIDRTYSAWLPSATIEFKP
VDWFRPYVSYSQSLRPPTILETFFAGARPGDSAGYEYAPNQSLRAEKATTYEIGANMSFD
GVLLDDDTLRIKMAAFRREVKDYIALGYLVTDQVFDRTYTSFVNLDGTTYMRGLELEGNY
DARSFWIGGSATVLKTEWPEKTQVFSNSTTTTSGEIVAWPGDVAPKMKLTLDGGMRFFDE
KFSLGARLNHVTPTQSRTLDTEGNLREITDPYTTVDLYGSYAFNDKATLRFAVNNLTDRK
YIPAASAYTAPGRTFIATMNVKF