Protein Info for Atu3383 in Agrobacterium fabrum C58

Annotation: rhizobicin secretion

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 transmembrane" amino acids 25 to 48 (24 residues), see Phobius details amino acids 55 to 80 (26 residues), see Phobius details amino acids 150 to 180 (31 residues), see Phobius details amino acids 253 to 270 (18 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 20 to 563 (544 residues), 828.3 bits, see alignment E=1.4e-253 PF00664: ABC_membrane" amino acids 33 to 284 (252 residues), 65.1 bits, see alignment E=8.6e-22 PF00005: ABC_tran" amino acids 355 to 501 (147 residues), 100.4 bits, see alignment E=1.4e-32

Best Hits

Swiss-Prot: 54% identical to PRSD_RHIME: Type I secretion system ATP-binding protein PrsD (prsD) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 100% identity to atu:Atu3383)

Predicted SEED Role

"ABC exporter for hemopore HasA, ATP-binding component HasD" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CF42 at UniProt or InterPro

Protein Sequence (615 amino acids)

>Atu3383 rhizobicin secretion (Agrobacterium fabrum C58)
MGFQNHQQTPPQSLTAAVVSPLKSTFLGVALVSGVVNILALTSPLFMLQVYDRVLASGSL
PTLVGLALLALGLYGFQCLLDIIRARVLIRIGEDFDMRYSGRVHDAVVRLPLVNRMPGDG
LQPLRDLDNVRGFLSGTGPTAFFDLPWMPLYLGLCFLFHVWIGVTALAGAVLLVSLTILT
NIFSQKPIRDTMVENMARNRQLEASRRNAEVVQAMGLGRRLGKRWQSSNEAYLAANRKAG
DVAGGLGNLAKSLRVVLQSAILAVGAWLVIRQEASGGVMIASSIMMGRALAPVDLAISNW
KSFVAARQSWARLRELFAQMPANAAAMALPKPEKELRVENVTIVPPGERKPTVTGLGFVV
TAGNALGIIGPSGSGKSTLARILTGAWMPAAGKVRLDGASFDQWDRETLGRHIGYLPQGV
ELFDGTIGENISRFDDNPDPEAIIAAARAAGAHELILRFEKGYDSDIGEAGSTLSAGQRQ
RIGLARALYGDPFIVVLDEPNANLDAEGEAAVVKAITSVKARGGIAVVVAHRPSAIGAVD
YILMMEDGRMKAFGPRDEVLSKVLRVPQAQAAKGFAASAQTVSPLRVVANVQPKPALVDD
VQDEESQEGDADAKH