Protein Info for Atu3374 in Agrobacterium fabrum C58

Annotation: amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 TIGR01891: amidohydrolase" amino acids 21 to 431 (411 residues), 249.7 bits, see alignment E=2.5e-78 PF01546: Peptidase_M20" amino acids 81 to 272 (192 residues), 29.8 bits, see alignment E=5.5e-11

Best Hits

KEGG orthology group: K12941, aminobenzoyl-glutamate utilization protein B (inferred from 100% identity to atu:Atu3374)

Predicted SEED Role

"Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit B" in subsystem p-Aminobenzoyl-Glutamate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CSA9 at UniProt or InterPro

Protein Sequence (480 amino acids)

>Atu3374 amidohydrolase (Agrobacterium fabrum C58)
MNRDAVMSIAAEIEAMKPDFTTLSDSIWDFAELKFEERQSARVLANALEENGFVVRRGVA
GMDTAFIGEFGQGNPIIAFLGEFDALAGMSQVAGVAEAKPLEPDATGHGCGHNLLGVGSL
MGAIALARHLKGNNLPGTVRYYGCPGEEGGSGKTFMVRAGLFDDADAALTWHPAPFNGVR
STNNLAVLEYFYRFKGVAAHASNAAHLGRSALDAVELMNVGVNFLREHMPQDCRVHYAIT
DTGGKAANVVQAKAEVLYLIRAPEIRQALDLAARVDKVARGAAMMTETEVEIVFDTASTN
LLPNITLETAMHENMVTLGPVAFDEADIAFAKSIQDTFTDEAIKSSIRLYQIKGDVFSNR
KIDGSTPLHLGLRDFEGQSHFRAGSTDVGDVSWVTPTAQCWTPAWAIGTNPHTWQVVAQG
KAPAAHKAMAHAAKAMASTGLALMTSPELLANAKKEWQEKTEGSRYVCPIPPDVMPGSHL