Protein Info for Atu3323 in Agrobacterium fabrum C58

Annotation: HlyD family secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 29 to 50 (22 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 30 to 452 (423 residues), 419.7 bits, see alignment E=6.7e-130 PF00529: CusB_dom_1" amino acids 42 to 409 (368 residues), 34.3 bits, see alignment E=4.7e-12 PF13533: Biotin_lipoyl_2" amino acids 79 to 104 (26 residues), 25.8 bits, see alignment (E = 1.8e-09) PF13437: HlyD_3" amino acids 301 to 406 (106 residues), 43.7 bits, see alignment E=1e-14

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 100% identity to atu:Atu3323)

Predicted SEED Role

"Secretion protein, HlyD family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CS59 at UniProt or InterPro

Protein Sequence (452 amino acids)

>Atu3323 HlyD family secretion protein (Agrobacterium fabrum C58)
MFTKKNAVTDVKPQGQLEWYSEVPRSIRLHSSIGLAVLLASFGGFGYWAGTAPLSSAIIA
QGSFVATGNNKVVQHLEGGIIKEMMVSEGDTVKVGDVLLTLDKTTALANERMFQLRRLRL
ETIVTRLRAEAQGEKSFKVPDIVMKEASDPDIKSIIQSQNVVFHSKLVKLDEQLNLINKN
IKSLEFRFAGYDGQKQSFDRQLALLTQERDSKERLAKDGVIRKTDMLALERAIADAMGDI
ARLTGEMNQSEAEIAKFKQEAVIAVNANKQAALDALEIAESDLDSVREQVRGAAEVLERT
VIRSPVNGTVIRAYYHTPGGVITTGKPIMEILPAHVPLILEAQVLRTSIDQLHEGQTAAI
RLSALNRRTTPVLNGKVFYVSADSIEENAGLQVKDVYIVRVQISDEEIAKVHNFHPVPGM
PADVLIQTSERTFFEYLTKPIADSMSRAFKER