Protein Info for Atu3168 in Agrobacterium fabrum C58

Annotation: sorbitol/mannitol ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 69 to 94 (26 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 152 to 177 (26 residues), see Phobius details amino acids 208 to 228 (21 residues), see Phobius details amino acids 261 to 282 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 101 to 288 (188 residues), 53.1 bits, see alignment E=1.7e-18

Best Hits

KEGG orthology group: K10228, sorbitol/mannitol transport system permease protein (inferred from 99% identity to atu:Atu4448)

MetaCyc: 64% identical to polyol ABC-type transporter permease component MtlF (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, permease component 1" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CES7 at UniProt or InterPro

Protein Sequence (290 amino acids)

>Atu3168 sorbitol/mannitol ABC transporter permease (Agrobacterium fabrum C58)
MATRNTSGLARVMLAPSVLLLLVWMIVPLAMTLWFSFQNYNLLNPANVSFAGLFNYQYFY
TDPAFFQSIWNTLLIVGGVLLITVVGGIAIALLLDNDIFGQGIVRIMIISPFFVMPPVAA
LVWKNMIMHPGYGVLADLSRFFGLQPVDWFAQFPLLSIIIIVAWQWLPFATLILLTALQS
LDGEQKEAAEMDGANFVNRFIYLTLPHLARAITVVILIQTIFLLGVYAEILVTTNGGPGY
ASTNLAFLIYRTALLGYDVGGASAGGIIAVVLANIVAIFLMRAVGKNLDR