Protein Info for Atu3077 in Agrobacterium fabrum C58

Annotation: beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00144: Beta-lactamase" amino acids 35 to 380 (346 residues), 257.5 bits, see alignment E=9.2e-81

Best Hits

Swiss-Prot: 44% identical to AMPC_PSYIM: Beta-lactamase (ampC) from Psychrobacter immobilis

KEGG orthology group: K01467, beta-lactamase [EC: 3.5.2.6] (inferred from 100% identity to atu:Atu3077)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CRJ2 at UniProt or InterPro

Protein Sequence (385 amino acids)

>Atu3077 beta-lactamase (Agrobacterium fabrum C58)
MKFNRRHIALAALVSTGLVTQASAADDARLKAITDAAIKPVMEKNGIPGLAVGISINGEN
HIFTYGVLSKSTEKPVTPQTLFELGSISKTFTVTLSTYAELNGQLSLSGKVSEYLPSMKG
KPFGDVALMHLGTHTAGGFPIQVPDDVKTEQQLMAYLKAWKPTYKAGTHRSYANPSIGML
GYITAKAMGQGFDGAMQDTLFPALGLKNTFTVVPKAKMDDYAQGYKRTGEPARVTPGVLS
SEAYGVKSTAEDMIRFVNANMGLEQLDGKIQQAITNTHAGYFSVGAMTQDMVWEQYTHPA
PLKTLRELNGGALLKTVPVSEISPPMKPREDVFINKTGSTNGFGAYVAFIPKEKLGIVIL
ANKNYPNEERVSAAYEILTALEKAQ