Protein Info for Atu3059 in Agrobacterium fabrum C58

Annotation: Na+/H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 32 to 51 (20 residues), see Phobius details amino acids 57 to 76 (20 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 113 to 136 (24 residues), see Phobius details amino acids 157 to 179 (23 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 214 to 231 (18 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 268 to 288 (21 residues), see Phobius details amino acids 305 to 326 (22 residues), see Phobius details amino acids 346 to 368 (23 residues), see Phobius details amino acids 379 to 404 (26 residues), see Phobius details TIGR00831: Na+/H+ antiporter" amino acids 10 to 521 (512 residues), 307.4 bits, see alignment E=8.8e-96 PF00999: Na_H_Exchanger" amino acids 16 to 404 (389 residues), 176.5 bits, see alignment E=4e-56

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 100% identity to atu:Atu3059)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CRH4 at UniProt or InterPro

Protein Sequence (527 amino acids)

>Atu3059 Na+/H+ antiporter (Agrobacterium fabrum C58)
MDGTHLFELVIAMFLAIIVLHYIAHRLGLPPSVALLAGGGTLAFVPGLPTISVNPELVLV
IFLPPLLLDGAWSISVDRLKRHVFGIASLAIGAVLFTTVIVAVVVHFLMPSLPWAACAAL
GAIVSPPDAVSARAVLERIRIPRRLQILLEGESLLNDASGLVLFRFAVAAAAGGVFSTVD
ALGEFFFLAVGGAAVGAFVGLLWVKTVRHLGDEYLMIAATAVLSWAAYILAEQAQTSGVI
ATVTAGLIASWHQHTVLSAATRMRGTSFWNVLVFLMEAMVFILIGLSLRDVVERGGGFGS
IASSMALPALAVLVTLVAARFVWIFASDLVIRLFHGLKLAHSKPLGPGAVTALGWAGMRG
VVTLALALSLPEDFPGRDFILVMAFAVIMGTVLIQGTTLGRIIAWAGLGGIEPERAPMTM
SEAEASMAQVQFTTVQGLAYDENGELIHPQLLKRYEHRLAASVKYAESTEKYSPLLHAHF
DVVLKAVAAGRKELIRLRREGQIDDETLRELEHDLDLEELTAISAKA