Protein Info for Atu3025 in Agrobacterium fabrum C58

Annotation: oligo alginate lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 776 PF16332: DUF4962" amino acids 50 to 452 (403 residues), 138.9 bits, see alignment E=2e-44 PF07940: Hepar_II_III" amino acids 492 to 710 (219 residues), 116.4 bits, see alignment E=1.5e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu3025)

MetaCyc: 55% identical to oligoalginate lyase (Sphingomonas sp. A1)
RXN-13034 [EC: 4.2.2.26]; 4.2.2.26 [EC: 4.2.2.26]; 4.2.2.26 [EC: 4.2.2.26]

Predicted SEED Role

"oligo alginate lyase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.2.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CEJ9 at UniProt or InterPro

Protein Sequence (776 amino acids)

>Atu3025 oligo alginate lyase (Agrobacterium fabrum C58)
MRPSAPAISRQTLLDEPRPGSLTIGYEPSEEAQPTENPPRFSWLPDIDDGARYVLRISTD
PGFTDKKTLVFEDLAWNFFTPDEALPDGHYHWCYALWDQKSATAHSNWSTVRSFEISEAL
PKTPLPGRSARHAAAQTSHPRLWLNSEQLSAFADAVAKDPNHCGWAEFYEKSVEPWLERP
VMPEPQPYPNNTRVATLWRQMYIDCQEVIYAIRHLAIAGRVLGRDDLLDASRKWLLAVAA
WDTKGATSRAYNDEAGFRVVVALAWGYDWLYDHLSEDERRTVRSVLLERTREVADHVIAH
ARIHVFPYDSHAVRSLSAVLTPACIALQGESDEAGEWLDYTVEFLATLYSPWAGTDGGWA
EGPHYWMTGMAYLIEAANLIRSYIGYDLYQRPFFQNTGRFPLYTKAPGTRRANFGDDSTL
GDLPGLKLGYNVRQFAGVTGNGHYQWYFDHIKADATGTEMAFYNYGWWDLNFDDLVYRHD
YPQVEAVSPADLPALAVFDDIGWATIQKDMEDPDRHLQFVFKSSPYGSLSHSHGDQNAFV
LYAHGEDLAIQSGYYVAFNSQMHLNWRRQTRSKNAVLIGGKGQYAEKDKALARRAAGRIV
SVEEQPGHVRIVGDATAAYQVANPLVQKVLRETHFVNDSYFVIVDEVECSEPQELQWLCH
TLGAPQTGRSSFRYNGRKAGFYGQFVYSSGGTPQISAVEGFPDIDPKEFEGLDIHHHVCA
TVPAATRHRLVTLLVPYSLKEPKRIFSFIDDQGFSTDIYFSDVDDERFKLSLPKQF