Protein Info for Atu2826 in Agrobacterium fabrum C58

Annotation: protease heat shock protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 30 to 47 (18 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 175 to 197 (23 residues), see Phobius details PF01435: Peptidase_M48" amino acids 69 to 278 (210 residues), 127.7 bits, see alignment E=2.4e-41

Best Hits

Swiss-Prot: 100% identical to HTPX_AGRFC: Protease HtpX homolog (htpX) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03799, heat shock protein HtpX [EC: 3.4.24.-] (inferred from 100% identity to atu:Atu2826)

Predicted SEED Role

"Probable protease htpX homolog (EC 3.4.24.-)" (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UBM5 at UniProt or InterPro

Protein Sequence (321 amino acids)

>Atu2826 protease heat shock protein (Agrobacterium fabrum C58)
MNMMRTAMLLAFMTALFMGVGFLIGGKGGMMIALLIAAGMNLFSYWNSDKMVLSAYRARE
IDEANAPEFFHMIRDLSQNAGLPMPKVYIYDSPQPNAFATGRNPENAAVAASTGLLERLT
PEEVAGVMAHELAHVQNRDTLTMTITATLAGAISMLGNFAFFFGGNRENNNNPLGFIGVL
VAMIVAPLAAMLVQMAISRTREYSADRRGAEICGNPLWLASALQKISGMAQQIHNDDAER
NPATAHMFIINPLSGERMDNLFSTHPNTENRVAALHAMAQEFSPRASTPPPSGDRPVRKS
GSVPTTGWRRGNENERKGPWS