Protein Info for Atu2808 in Agrobacterium fabrum C58

Annotation: cobyric acid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 PF13500: AAA_26" amino acids 5 to 229 (225 residues), 50 bits, see alignment E=5e-17 TIGR00313: cobyric acid synthase CobQ" amino acids 6 to 479 (474 residues), 425.3 bits, see alignment E=1.6e-131 PF01656: CbiA" amino acids 6 to 238 (233 residues), 73.2 bits, see alignment E=2.9e-24 PF07685: GATase_3" amino acids 255 to 437 (183 residues), 187.6 bits, see alignment E=3e-59

Best Hits

Swiss-Prot: 100% identical to COBQ_AGRFC: Cobyric acid synthase (cobQ) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02232, adenosylcobyric acid synthase [EC: 6.3.5.10] (inferred from 100% identity to atu:Atu2808)

Predicted SEED Role

"Cobyric acid synthase (EC 6.3.5.10)" (EC 6.3.5.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.5.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UBP3 at UniProt or InterPro

Protein Sequence (485 amino acids)

>Atu2808 cobyric acid synthase (Agrobacterium fabrum C58)
MTARVLMFQGTGSDVGKSLMVAGLARAFTRRGLSVVPFKPQNMSNNAAVTADGGEIGRAQ
ALQARAAGVPLSVHMNPVLLKPQSETGAQVVVQGKIVGSAKAADYQHMKAGLMPRVLDSF
EHLKQLADLVLVEGAGSASEINLRANDIANMGFARAADAPVILIGDIDRGGVIASLVGTR
EVLDDDDAAMIEGFIVNRFRGDPALFSDGMRMIAEKTDWSSIGLLPHFSDAAKLPAEDAL
GLSGPAQRKPSAKIRIAVPILPHISNFDDLDPLDMEPDVELIRVRPGETIPADCRLVLLC
GSKSTIADLAVLKDAGLDIDIKAHVRRGGYVLGLCGGYQMLGKTVADPDGIEGPPATVEG
LGLLDVDTVLTGDKRLVSVRGTSFDGVGLSGYEMHVGETTGIAGSLVFSTIDGHADGTIS
PDGRVFGTYIHGLFADDRQRSAWLERLGGQGTDLNYDAQVDAVLDRLAAHMEQHLDLDRL
LAIAR