Protein Info for Atu2705 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein (protein)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 15 to 37 (23 residues), see Phobius details amino acids 49 to 69 (21 residues), see Phobius details amino acids 138 to 169 (32 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 8 to 552 (545 residues), 812.7 bits, see alignment E=7.6e-249 PF00664: ABC_membrane" amino acids 16 to 276 (261 residues), 63.7 bits, see alignment E=2.3e-21 PF00005: ABC_tran" amino acids 343 to 489 (147 residues), 101.3 bits, see alignment E=7.6e-33

Best Hits

Swiss-Prot: 56% identical to PRSD_RHIME: Type I secretion system ATP-binding protein PrsD (prsD) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 100% identity to atu:Atu2705)

Predicted SEED Role

"CELL PROCESSES; Transport of small molecules; amino acids, amines, peptides"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CWF9 at UniProt or InterPro

Protein Sequence (577 amino acids)

>Atu2705 ABC transporter, nucleotide binding/ATPase protein (protein) (Agrobacterium fabrum C58)
MFLFNSFLTKNKSTFFAVGLASALMNILNLSGSLFMLEVYDRILPSKSIPSLVALVVLLI
VLYAFLMGFDALRGRILARISDNMDDALNQKLFRASISAPLLASSKIDGLQIVGDLDQIR
QFLSGPGPAAFFDIPWLPIYLLICFALHPWIGFAVLGGAVVLVVLTLLTNWLTERATKQA
YTARGQRNVLVGSSQRNIESIKTMGMMGAVTSMWDELHSKYRSVTLSTSDTAGMLGAMSR
TFRLLLQSGVMAIGAVLVIDGHASAGSIIAGSILSAKALGPVEHAIANWRSFMTARQGWK
RVNEFLELVPEPAPPLSLPRPQFTVAVDRVTGGPPNGARDTVADISFTLNAGDGLGIIGP
SASGKSTLARLMTGIWPYERGSVRFDGAALNQWDFEFLGKSIGYMPQQVELMPGTVAQNI
ARFDRNATAESIVAAAKAAQVHELILNLPNGYDTSIGDRGEALSGGQKQRIGLARALFGE
PFFVLLDEPNSNLDSEGEAALRNAIGDIRARGGIVVVIAHRPSALESINMVMVMSNGRML
RFGTKEEVLAQILRQNIRQVPEGEETRKIENRVSENG