Protein Info for Atu2467 in Agrobacterium fabrum C58

Annotation: ABC transporter, substrate binding protein (iron)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13531: SBP_bac_11" amino acids 40 to 299 (260 residues), 36.4 bits, see alignment E=1e-12 PF13416: SBP_bac_8" amino acids 54 to 312 (259 residues), 64 bits, see alignment E=4.1e-21 PF13343: SBP_bac_6" amino acids 131 to 322 (192 residues), 34.9 bits, see alignment E=2.4e-12

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 100% identity to atu:Atu2467)

Predicted SEED Role

"ABC-type Fe3+ transport system, periplasmic component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CWZ6 at UniProt or InterPro

Protein Sequence (359 amino acids)

>Atu2467 ABC transporter, substrate binding protein (iron) (Agrobacterium fabrum C58)
MIFSMRICLFLCLCLCMASPALAQVAVFPALSGKTDAQTLVVYSSLDEPLATPMIEGFQK
ANPDIAVHYEDMLTGEIYDRIVKETDAGKKTADFAFSSAMDLQVKLSNDGYAQRSDLAMS
ARWPAWANWRNTAYALTFEPAVFVYHKPSFTTEKPPATRAEFVDYLERHAKEVHGRIATY
DIERSGVGFLFMSRDQEQFGDIWSVIKAMGAAGVKVYSTSSAILERVSDGRFVLGYNILG
SYAADWASRHPDVGIVLPKDYTVVMSRIGLVPEAAANPELGRRYLEFFMSKEGQTIMARQ
LQIPAVSPEVAGENTANTMQAIHGAQLRPVPVSPGLMVYLDQVKRSRLIERWNEALRSQ