Protein Info for Atu2365 in Agrobacterium fabrum C58

Annotation: ABC transporter, substrate binding protein (amino acid)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00497: SBP_bac_3" amino acids 29 to 250 (222 residues), 131.9 bits, see alignment E=1.3e-42 PF10613: Lig_chan-Glu_bd" amino acids 70 to 113 (44 residues), 33.7 bits, see alignment 3.5e-12

Best Hits

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to atu:Atu2365)

Predicted SEED Role

"Nucleoside ABC transporter, permease protein 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CHX9 at UniProt or InterPro

Protein Sequence (256 amino acids)

>Atu2365 ABC transporter, substrate binding protein (amino acid) (Agrobacterium fabrum C58)
MKFFATLLAGTAFAVSAFTASADVRFGIMNESYPPFFAKDASGKWQGWEIDLMDAVCAEM
KEKCSIVELSWDGLIPALQTKKFDVIWSSMSNTQEREKVIDFTNKYYNTPSKLIGAKGEK
PGAAPEDVKGKTIGIQVATIQSEYYKKYFAAVADEKTYQTLDEAFQDLAAGRIDYVFGDS
LVLDAFVKSDAGKDCCADMGNVADDKEIMGLGVSGGLRKDDTELKNKLNAAIAAVRASGK
YDEITKKYFSFDIYGN