Protein Info for Atu2279 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein (proline/glycine betaine)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 TIGR03415: choline ABC transporter, ATP-binding protein" amino acids 5 to 289 (285 residues), 540.9 bits, see alignment E=7.9e-167 PF00005: ABC_tran" amino acids 45 to 196 (152 residues), 101.2 bits, see alignment E=8.2e-33

Best Hits

KEGG orthology group: K02000, glycine betaine/proline transport system ATP-binding protein [EC: 3.6.3.32] (inferred from 100% identity to atu:Atu2279)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProV (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.32

Use Curated BLAST to search for 3.6.3.32

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CI32 at UniProt or InterPro

Protein Sequence (348 amino acids)

>Atu2279 ABC transporter, nucleotide binding/ATPase protein (proline/glycine betaine) (Agrobacterium fabrum C58)
MSDAIIFGNVDIVFGDRPDAALALIDKGSTRDEINAQTGLVLGVANASLSVSEGEILVLM
GLSGSGKSTLVRAVNGLAPVVRGSVSVKTKSGYVDPYRCPAKALRDLRMHTVSMVFQQFG
LLPWRNVADNVGFGLELSGVPEAERKRMVAEQLELVNLSAWADRKVGELSGGMQQRVGLA
RAFATGAPILLMDEPFSALDPLIRSRLQDELLEFQSRLKKTILFVSHDLDEAFRIGNRIA
MMEGGHIIQCGTPQQIVRQPATPYVADFVQNMNPISMLTAADVMKRGVDERSGRLTVAAT
ALPSSPLIDILDALSKHAGAIGVVDNGAIIGTISADEVVAGLTRHRKK