Protein Info for Atu2273 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 TIGR03139: 7-cyano-7-deazaguanine reductase" amino acids 23 to 133 (111 residues), 150.4 bits, see alignment E=8.9e-49 PF14489: QueF" amino acids 58 to 135 (78 residues), 108.1 bits, see alignment E=1.1e-35

Best Hits

Swiss-Prot: 100% identical to QUEF_AGRFC: NADPH-dependent 7-cyano-7-deazaguanine reductase (queF) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K09457, 7-cyano-7-deazaguanine reductase [EC: 1.7.1.13] (inferred from 100% identity to atu:Atu2273)

Predicted SEED Role

"NADPH dependent preQ0 reductase (EC 1.7.1.13)" (EC 1.7.1.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UD54 at UniProt or InterPro

Protein Sequence (154 amino acids)

>Atu2273 hypothetical protein (Agrobacterium fabrum C58)
MSVTDVSGLSQLGTKVDTPESPEKAVLEKVPNGNAGTDYVVRFTAPEFTSLCPMTGQPDF
AHIVIDYIPGDFLVESKSLKLFLQSFRNHGAFHEDCSVYIAKRLVELLQPKWLRIGAYWY
PRGGIPIDVFWQTGAAPEGVWLPDQGVAPYRGRG