Protein Info for Atu2245 in Agrobacterium fabrum C58

Annotation: Na+/Pi-cotransporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 51 to 75 (25 residues), see Phobius details amino acids 87 to 110 (24 residues), see Phobius details amino acids 131 to 150 (20 residues), see Phobius details amino acids 162 to 186 (25 residues), see Phobius details amino acids 191 to 220 (30 residues), see Phobius details amino acids 245 to 263 (19 residues), see Phobius details amino acids 282 to 302 (21 residues), see Phobius details PF02690: Na_Pi_cotrans" amino acids 16 to 150 (135 residues), 110.5 bits, see alignment E=7e-36 TIGR01013: sodium-dependent inorganic phosphate (Pi) transporter" amino acids 71 to 521 (451 residues), 378.6 bits, see alignment E=2.4e-117 PF01895: PhoU" amino acids 341 to 421 (81 residues), 39.6 bits, see alignment E=5.8e-14 amino acids 446 to 529 (84 residues), 38.1 bits, see alignment E=1.6e-13

Best Hits

KEGG orthology group: K03324, phosphate:Na+ symporter (inferred from 100% identity to atu:Atu2245)

Predicted SEED Role

"Sodium-dependent phosphate transporter" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXJ0 at UniProt or InterPro

Protein Sequence (550 amino acids)

>Atu2245 Na+/Pi-cotransporter (Agrobacterium fabrum C58)
MQSTIVIVNLLGAVALLLFGLAQVKDGVTRAFGMKLRSVLATGTQNGPRSFFSGFFATVA
LQSSTATALTVASFAERDLIKPRMAQVVLLGANVGTAVTAWIVAAGVEWLSPLLILAGII
LKKGSSNARQGGGTAVIGIGLMLLSLHLLSGATEPMRASPALGVFIGLLDGAWPVALIFS
AVLAFVSSSSLAVVVLILSLTATGTLSTGLIIVLILGANLGGAIPPVIATLSGPASARRI
TIGNLVVRTIGCLIAMPLASYGATYLQQLPLSPAKLPVDAHLIFNLILATLAWPFSGLIS
DLMAKLVPGDPKAEDGPNFLDQQALDVPVVALANATREVLSVGDSIERMLIRAENAFKHN
DLAPLQEVALLEKKVDRRQQEVKVYLSQLGRKGLTDEEARRSIAIIDYAINLEHIGDIIE
KGICEQIRKKVLNSFKFSDDGYEELKTLFDMTIENLRAAQSILVTGDFELARRLMESKVD
IRRLEKQSSNRHLERLRDGLAESMQTSSLHLDMLRDLKRINAHIVTVAHPILDESGVLIE
SRLRYAEPRA