Protein Info for Atu2154 in Agrobacterium fabrum C58

Annotation: MFS permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 21 to 49 (29 residues), see Phobius details amino acids 57 to 81 (25 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 117 to 117 (1 residues), see Phobius details amino acids 119 to 144 (26 residues), see Phobius details amino acids 157 to 181 (25 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 248 to 272 (25 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details amino acids 313 to 333 (21 residues), see Phobius details amino acids 340 to 362 (23 residues), see Phobius details amino acids 376 to 399 (24 residues), see Phobius details amino acids 405 to 424 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 25 to 230 (206 residues), 70.4 bits, see alignment E=1.5e-23 PF07690: MFS_1" amino acids 36 to 387 (352 residues), 99.4 bits, see alignment E=2.1e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2154)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CI86 at UniProt or InterPro

Protein Sequence (443 amino acids)

>Atu2154 MFS permease (Agrobacterium fabrum C58)
MSPTTTPAAARPLNSQDFRTLGLSALGGALEFYDFIIFVFFATVIGHLFFPPEMPDWLVM
IQTFGIFAAGYLVRPLGGIVLAHYGDRYGRKRVFAFSILLMALSTLGMALMPTYATIGVA
APILLIILRMLQGAAIGGEVPGAWTFVAEHVPFRRVGLACGFLTSGLSFGIMLGSLIAFA
INSLFTPEDVAGYAWRIPFLLGGVFGLIAVYLRRWLEETPIYMEMKKSKSLTDKLPLGLV
LKHHRRGVIISALLTWVLSAAIVVTTLMTATFLQKLYGYTPTQALAGTSFGTLFLIFGVI
IAGALIDRVGSGIFFMGASIFFGIATFTFYSYAGTSLETMFVLYGVMGLSVGMAGAVPYV
MVRAFPASVRFSGLSFAYNVSYAVFGGLTPIGVTTALAINPMAHAWYLVFIAFLAFAIGL
YLHLRGSEVESHVGIEELAALRS