Protein Info for Atu2143 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (amino acid)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 transmembrane" amino acids 26 to 48 (23 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details amino acids 259 to 280 (22 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details amino acids 389 to 413 (25 residues), see Phobius details amino acids 427 to 447 (21 residues), see Phobius details amino acids 457 to 475 (19 residues), see Phobius details PF13520: AA_permease_2" amino acids 28 to 466 (439 residues), 116.2 bits, see alignment E=1.9e-37 PF00324: AA_permease" amino acids 43 to 470 (428 residues), 120.6 bits, see alignment E=7.9e-39

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2143)

Predicted SEED Role

"permease, possibly an amine"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXS4 at UniProt or InterPro

Protein Sequence (504 amino acids)

>Atu2143 ABC transporter, membrane spanning protein (amino acid) (Agrobacterium fabrum C58)
MDSSSSGVSYKKADASYFEKRGLSRYAGVWSLWALGVGAVISGHFSGWNFGFSTGGWGGM
LVAGIIIAIMYLGLTFSIAEMSPALPHTGAAYSFARTAMGPWGGFVTGLCENVEYVLTPA
VVVTFITAYVNSILGLDPAYSPFVWIVFYAIFLALNVFGLELSFKVTLVITLISLAVLVF
FWISAIPNIDFSRFALNIGVGPDGKAVELPEGGGSFFPFGFSGVLATLPFAVWLFLAIEQ
LPLAAEESVDPKRDMPKGIILGMVTLMVSAFMIVLLNPSLPGVGAFHLSSSLEPLLDGFK
AIYGDGGVVLLGLVALTGLIASFHTILYAQGRQIYSLSRAGYFPTVLSITHSKYRTPYVA
NITGAIVGLAVMLVIWFSLGAEQGGSIIGSVLLNMAVFGAMFSYIMQAISFILLRKNLPN
IERPFRSPFGIPGALLTIIIAIVTLLYQIQDPNFTKGVLWVAVWFAVAIAYFAFVGRHRL
ILSPEEEFALEHKQAAVAAAAAKA