Protein Info for Atu2125 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 TIGR03719: ATP-binding cassette protein, ChvD family" amino acids 4 to 547 (544 residues), 931.6 bits, see alignment E=1.5e-284 PF00005: ABC_tran" amino acids 22 to 185 (164 residues), 88.5 bits, see alignment E=1.3e-28 amino acids 334 to 467 (134 residues), 87.1 bits, see alignment E=3.6e-28 PF12848: ABC_tran_Xtn" amino acids 224 to 296 (73 residues), 53.5 bits, see alignment E=4.1e-18

Best Hits

Swiss-Prot: 60% identical to ETTA_MYCTO: Energy-dependent translational throttle protein EttA (ettA) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 100% identity to atu:Atu2125)

Predicted SEED Role

"ABC transporter, ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U559 at UniProt or InterPro

Protein Sequence (549 amino acids)

>Atu2125 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58)
MARQFIYHMAGLNKSYGAKKVLENVHLSFYPDAKIGILGPNGAGKSTVLKIMAGLDKEYT
GEAWLAEGATLGYLEQEPKLDENKTVMENVMEGVASKTAIVDRYNELMMNYSDETADEGA
KLQDMIDSQNLWDLENQVEMAMDALRCPPGDSAVTGLSGGERRRVALCKLLLSQPDLLLL
DEPTNHLDAETIAWLEKHLRDYPGAVMMITHDRYFLDNVTGWILELDRGRGIPYEGNYSA
YLQAKAKRMQQEAREDASRQKAISREQEWIASSPKARQTKSKARIRAYDELVEAAENRRP
GDAQIVIPVAERLGRVVIEAENLTKSYGDRVLIENLTFKLPPGGIVGVIGPNGAGKTTLF
RMITGQEQPDSGSVTVGETVHLGYVDQSRDTLAGDKTVWEEISGGNDIIKLGKFEVNSRA
YCGAFNFKGGDQQQKVGNLSGGQRNRVHLAKMLKAGGNVLLLDEPTNDLDTETLAALEEA
LEAFAGCAVIISHDRMFLDRLATHILAFEGDSHVEWFEGNFEDYEKDKVRRLGPESIKPG
RVSYKRLTR