Protein Info for Atu2121 in Agrobacterium fabrum C58

Annotation: glycosyl hydrolase/lysozyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details PF01183: Glyco_hydro_25" amino acids 81 to 259 (179 residues), 203.1 bits, see alignment E=2.4e-64

Best Hits

KEGG orthology group: K07273, lysozyme (inferred from 100% identity to atu:Atu2121)

Predicted SEED Role

"Lyzozyme M1 (1,4-beta-N-acetylmuramidase) (EC 3.2.1.17)" (EC 3.2.1.17)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXU5 at UniProt or InterPro

Protein Sequence (283 amino acids)

>Atu2121 glycosyl hydrolase/lysozyme (Agrobacterium fabrum C58)
MRKSGDTARRFAAAGWATIIIRVPMRLRFSALLSALLLVSGCTSTSYDLLETASVSRPKF
SDTDPQDFGVNNPHRHEVHGIDVSKWNGDVDWQTVRKSGVSFVFIKATEGSDRIDPKFGD
HWRSAASANILHAPYHFYYFCSTADAQADWFISNVPKEAVTLPPVLDVEWNPSSPTCKTR
PAPGIVRAEMQRFLDRLEAHYGKRPIIYTSVDFHRDNLVGQFKDYHFWVRSVAAHPAKIY
EDRKWAFWQYTATGVVPGVNGPTDINVFAGSEKNWRKWIASAK