Protein Info for Atu2070 in Agrobacterium fabrum C58

Annotation: aminopeptidase P

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 PF01321: Creatinase_N" amino acids 17 to 139 (123 residues), 57 bits, see alignment E=6.1e-19 amino acids 183 to 296 (114 residues), 22.3 bits, see alignment E=3.2e-08 PF16189: Creatinase_N_2" amino acids 158 to 318 (161 residues), 126.6 bits, see alignment E=1.9e-40 PF00557: Peptidase_M24" amino acids 325 to 538 (214 residues), 165.9 bits, see alignment E=2.3e-52 PF16188: Peptidase_M24_C" amino acids 549 to 609 (61 residues), 87 bits, see alignment 1.3e-28

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to atu:Atu2070)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CIC1 at UniProt or InterPro

Protein Sequence (613 amino acids)

>Atu2070 aminopeptidase P (Agrobacterium fabrum C58)
MFQTFDNKSAPQFGKARVEALRAGFDALGIDGFLVPRADEYQGEYVPECAERLSWLTGFT
GSAGIALVTRAQAVVFVDGRYTTQLKSQVDQSVFTGGDLVGAPPSVWLSEHAAQGFRLGI
DPWLHTGAELKRLEKALAGKGGSVVLLEKNPLDALWQDRPAEPLEPVVIQPEAFTGILAK
EKIASLAETVSAKGADALLVTDPSSIAWIFNIRGNDVPHTPHPLARGIIYADGKADIFLD
KRKTGIEAEAYLAQLATQLPPSKIADRLHAIASAKGRVMVDADLTPVALTGAITAAGGSL
IEEADPVRLPRARKNKAELAGSAAAHVQDGAAMVEYLCWLDRQQPGSVTEIAAVKALEAA
RAKVGQAMQNPLKDVSFDTISGAGDHAAIIHYRVTTDTDRILADGEMFLVDSGAQYVNGT
TDITRTVAIGTVPEEQRRFFTLVLKGVIAISAARFPKGTRGCDLDPLARIALWKAGADYA
HGTGHGVGSYLSVHEGPQRIARLSTQELLPGMILSNEPGYYRPGAFGIRIENLIYVREAE
EVAGGDQPMFSFETLTWCPIDRRLVVVSLLTDEELDWLNAYHADVLEKLSPLITDEEVKA
WLVAATKPLERAA