Protein Info for Atu2061 in Agrobacterium fabrum C58

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 transmembrane" amino acids 99 to 111 (13 residues), see Phobius details PF00561: Abhydrolase_1" amino acids 34 to 256 (223 residues), 104 bits, see alignment E=2.8e-33 PF12146: Hydrolase_4" amino acids 35 to 254 (220 residues), 74.1 bits, see alignment E=2.9e-24 PF12697: Abhydrolase_6" amino acids 36 to 259 (224 residues), 83.9 bits, see alignment E=6.8e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu2061)

Predicted SEED Role

"Biotin synthesis protein BioH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CXY9 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Atu2061 hydrolase (Agrobacterium fabrum C58)
MTAPSLDNWEKRKRFVELPRKRQMAFIDTGGPGPVLLMLHGFSDTSRSFSIIEPYFQEYR
LIAPDLPGHGASSVGHGFHVADFAETIDRFLTLMGVSRFFVLGHSMGAMTAIELAARRSS
SVRGLALISGTLEPDFGTESKLARDILALRDPIKPAGGFLHDWYSCSRPVNEEFLFRMKR
DAANMAATTWHGVLKAFAETDLHYSASKINVPVLCLAGSEDPLFDDSHRQQLFEAFPLAQ
TVTMPGHGHNPHWENPQGVSTLVTEFFAEVMTDASPVRVETAADKR