Protein Info for Atu2040 in Agrobacterium fabrum C58

Annotation: phosphoserine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details TIGR00338: phosphoserine phosphatase SerB" amino acids 75 to 285 (211 residues), 220.3 bits, see alignment E=2.3e-69 PF00702: Hydrolase" amino acids 81 to 255 (175 residues), 60.5 bits, see alignment E=4.4e-20 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 82 to 252 (171 residues), 112.5 bits, see alignment E=2.2e-36 PF12710: HAD" amino acids 84 to 252 (169 residues), 70.3 bits, see alignment E=4.5e-23 PF08282: Hydrolase_3" amino acids 219 to 275 (57 residues), 41.4 bits, see alignment E=2.2e-14

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 100% identity to atu:Atu2040)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CID2 at UniProt or InterPro

Protein Sequence (296 amino acids)

>Atu2040 phosphoserine phosphatase (Agrobacterium fabrum C58)
MALVATLIANPSNPVLTAALGEAAAKAVNASGLYWLADGIACDIALPLGTAAEQARSAIA
AALIGKPIDIVIQEQDQRRKKLLIADMDSTMIGQECIDELAAEVGLKDKVSAITARAMNG
EIAFEPALRERVALLKGLPVSVIDDVIEKRITLTSGGKELIATMKAKGYYTALVSGGFTV
FTNRVAAMLGFDENRANLLGEANGELDGTVAEPILGKQAKVDALNDIAARLGISSEEAMA
VGDGANDLGMLHVAGAGVALHAKPAVAAEAQMRIDHGDLTALLYIQGYRKTDFVIP