Protein Info for Atu1906 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 55 to 82 (28 residues), see Phobius details amino acids 90 to 133 (44 residues), see Phobius details amino acids 139 to 162 (24 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 198 to 215 (18 residues), see Phobius details amino acids 224 to 245 (22 residues), see Phobius details PF01061: ABC2_membrane" amino acids 6 to 216 (211 residues), 114 bits, see alignment E=3.6e-37

Best Hits

Swiss-Prot: 42% identical to YADH_SHIFL: Inner membrane transport permease YadH (yadH) from Shigella flexneri

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 100% identity to atu:Atu1906)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CIG7 at UniProt or InterPro

Protein Sequence (253 amino acids)

>Atu1906 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MNFEAIKSIYLFEMARTRRTLLQSVVSPVISTSLYFIVFGTAIGSRIQEVGGVSYGAFIT
PGLIMLTLLTQCISNGSFGIYFPKFTGTVYEILSAPVSMTEIVAGYVGAAATKGLMIGTI
ILITASFFVDITIAHPFMMVLFFVLTAVSFSLFGFIIGIWATNFEQLNLIPMLVVPPLTF
LGGSFYSIDMLPPFWQTVSHFNPVLYLISGFRWSFYEIADVNPVISLAMITLFLAVCLGV
VAWMFKTGYRLRN