Protein Info for Atu1738 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 49 to 74 (26 residues), see Phobius details amino acids 135 to 152 (18 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 246 to 248 (3 residues), see Phobius details amino acids 252 to 284 (33 residues), see Phobius details PF00664: ABC_membrane" amino acids 17 to 287 (271 residues), 184.4 bits, see alignment E=3.7e-58 PF00005: ABC_tran" amino acids 349 to 498 (150 residues), 121.9 bits, see alignment E=3e-39

Best Hits

Swiss-Prot: 62% identical to YWJA_BACSU: Uncharacterized ABC transporter ATP-binding protein YwjA (ywjA) from Bacillus subtilis (strain 168)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to atu:Atu1738)

Predicted SEED Role

"ABC transporter, nucleotide binding/ATPase protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CYM9 at UniProt or InterPro

Protein Sequence (577 amino acids)

>Atu1738 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58)
MLRRFFAYYRPYRGLFILDFSCAVLSGVLELGFPMAVKAFVDVLLPGGQWGIILAASVGL
LVIYVLNTGLMATVTYWGHMLGINIETDMRRLAFDHLQKLSFRYFDNQKTGHLVGRLTKD
LEEIGEVAHHGPEDLFIAIMTFIGAFLLMMSVNVQLALVTAAVVPVTAWVTSRYGGRMTQ
NFRALYGRVGDFNARIEENVGGMRVVQAFANEDHERSLFEKDNQKYRRTKLDAYKIMAAS
TSLSYMSMRLTQMIVMICGAWFVLNGSLTEGGFVGFLLLVGVFFRPVEKINSVIETYPKG
IAGFRRFTELLDTAPDIVDAPDAIDAPALSGAIEYRHVGFGYAEGKRVLDNIDLKISAGE
TVAFVGPSGAGKTTLCSLLPRFYDVTSGSITIDGIDIRKMKLASLRNQIGIVQQDVFLFG
GTIRENIEYGRLGASDEEIMDAARRARLDGVIEAMPLGLDTVIGERGVKLSGGQKQRLAI
ARMFLKNPPILILDEATSALDTETERAIQQSLTELAKGRTTLVIAHRLATIRDASRIVVV
DQTGIAETGAHAELLAAKGHYSRLHEAQFSGHLAGLS